Pathological changes in the osteoarticular system during COVID-19 drug therapy (review of literature)

The recommended drugs for the treatment of COVID-19 are, on one hand, experimental in nature, but at same time, they have many side effects that cause long-term complications organs and systems, including osteoarticular. Based analysis modern domestic foreign literature, to determine effect not only new coronavirus infection COVID-19, also used treat it, human osteoarticular system. In course study, a scientific search was made publications electronic databases PubMed, MedLine e-Library period from January 2000 October 2021 main keywords. Due successive “waves” pandemic, number patients receiving non-specific therapy, corticosteroids, will increase coming years. Preliminary data similar trends during Sars-COV-1 epidemic 2003 show pathogenesis Sars- Cov-2 its with high doses corticosteroids may risk osteonercosis patients, which inevitably lead an orthopedic diseases middle age group, young near future. Currently, studies are required aimed stratification, studying damage musculoskeletal system after effectiveness preventive therapeutic measures such patients.